Polynucleotides & Skin Boosters

What Are Polynucleotides?

Polynucleotides (PNs) are a cutting-edge skin regenerative treatment derived from purified fragments of DNA, often sourced from salmon or trout. These naturally occurring molecules stimulate the skin’s ability to repair, regenerate, and deeply hydrate itself—making them a powerful option for skin rejuvenation and healing.

When introduced into the skin through precise injections or advanced techniques, polynucleotides work by:

  • Boosting fibroblast activity – encouraging collagen and elastin production

  • Improving hydration at a cellular level by increasing hyaluronic acid synthesis

  • Reducing inflammation and oxidative stress, promoting skin healing

  • Enhancing skin tone, texture, and elasticity over time

Unlike traditional dermal fillers which simply add volume, polynucleotides focus on restoring skin quality from within. The result? Smoother, firmer, brighter, and more youthful-looking skin with a natural finish.

Ideal For:

  • Fine lines and wrinkles

  • Dull, tired, or crepey skin

  • Under-eye rejuvenation and dark circles

  • Scarring or acne scarring

  • Skin affected by sun damage or stress

  • Those seeking a more natural approach to skin regeneration

Polynucleotide treatments can be used as a standalone skin booster or combined with other aesthetic treatments like microneedling for enhanced results. They're suitable for all skin types and are especially popular for delicate areas like the tear troughs and neck.

Polynucleotide Treatments

Polynucleotide Skin Regeneration Treatments

Reveal healthier, firmer, and more radiant skin with our advanced polynucleotide therapy. We offer two of the most trusted and clinically effective options: Vitaran and Plinest.

What Are Polynucleotides?

Polynucleotides (PNs) are purified fragments of DNA that stimulate your skin’s natural repair processes. Derived from salmon DNA and processed to the highest medical standards, these molecules promote:

  • Deep hydration
  • Collagen and elastin stimulation
  • Tissue repair and regeneration
  • Brighter, firmer, and more youthful skin

Unlike fillers, PNs don’t just “fill”—they regenerate. Ideal for anyone wanting a natural, glowing result with minimal downtime.

Vitaran

Vitaran is a next-generation polynucleotide treatment designed to renew and revitalise the skin from within. With ultra-purified salmon DNA fragments, Vitaran enhances skin function at the cellular level.

Key benefits:

  • Stimulates collagen and elastin for firmer skin
  • Improves tone, texture, and hydration
  • Safe for all skin types, including sensitive skin
  • Especially effective for under-eye, face, and neck rejuvenation

Best results are seen with a course of treatments, spaced 2–3 weeks apart.

Plinest

Plinest is one of the most clinically studied and trusted polynucleotide products in regenerative aesthetics. Developed in Italy using PN-HPT™ technology, it is known for its superior skin repair and anti-inflammatory properties.

Ideal for:

  • Tear troughs and fine lines
  • Acne scarring or post-inflammatory marks
  • Sensitive, inflamed, or stressed skin
  • Enhancing results of microneedling, PRP, or laser

Plinest is often considered the gold standard in skin regeneration, with visible improvement in skin quality, smoothness, and elasticity.

Which Treatment Is Right for Me?

Both Vitaran and Plinest offer powerful skin regeneration, and the choice depends on your individual skin concerns, treatment area, and skin type. During your consultation, we will assess your needs and recommend the best protocol for you.

Results build over time, and clients often complete a series of 3–4 treatments for optimal improvement.

Our services.

  • Polynucleotide Under Eyes

    Polynucleotide injections using Vitaran or Plinest target the under-eye area to deeply hydrate, repair, and improve skin quality. Helps reduce dark circles, fine lines, and puffiness while boosting collagen and tissue regeneration.

    Per session: £150

    3 session: £325

  • Polynucleotides Full Face

    Polynucleotide injections for the full face using Vitaran or Plinest help stimulate collagen production, improve skin hydration, and reduce fine lines. This treatment enhances skin texture and firmness, leaving the face looking rejuvenated and refreshed.

    Per session: £300

    3 session: £700

  • Polynucleotides Full Face & Neck

    Polynucleotide injections for the full face and neck using Vitaran or Plinest help stimulate collagen production, improve skin hydration, and reduce fine lines. This treatment enhances skin texture and firmness, leaving the face looking rejuvenated and refreshed.

    Per session: £350

    3 sessions: £750

  • Polynucleotides Neck Only

    Polynucleotide injections using Vitaran or Plinest for the neck area help improve skin hydration, stimulate collagen production, and reduce the appearance of fine lines. This treatment enhances skin elasticity and texture, promoting a smoother, firmer, and rejuvenated neckline.

    Per session: £200

    3 sessions: £500

  • Polynucleotides Under Eye + Microneedling Full Face w/Mesotherapy Ampoule

    Combine Polynucleotides under eyes with Microneedling w/ Mesotherapy ampoule for a comprehensive approach to treating your skin.

    For more information on Microneedling w/Mesotherapy ampoule click here.

    Per session: £275

    3 sessions: £650

  • Polynucleotides Under Eye + Microneedling Full Face with Exosomes or Polynucleotides

    Combine Polynucleotides under eyes with Microneedling w/ Exosomes or Microneedling w/ Exosomes+ Polynucleotides for a comprehensive approach to treating your skin.

    For more information on Microneedling w/Exosomes or Microneedling with/Exosomes+Polynucleotides click here.

    Per session: £325

    3 sessions: £750

Injectable Skin Boosters

Skin boosters are an advanced injectable treatment designed to hydrate, rejuvenate, and improve the overall appearance of the skin. Made from hyaluronic acid or polynucleotides, these treatments help restore moisture, enhance skin elasticity, and promote a natural glow. Unlike traditional dermal fillers, skin boosters are injected into the skin’s deeper layers, providing long-lasting hydration and improving skin texture.

The treatment works by stimulating collagen production, which results in smoother, more youthful-looking skin. Skin boosters are ideal for individuals looking to enhance skin quality, reduce fine lines, and combat dryness. They can be used on various areas of the face, neck, décolletage, and hands.

At Virgo & Co. Skin and Aesthetics, we offer polynucleotide skin boosters, which help repair and regenerate the skin, leaving you with revitalized, plump, and glowing skin.

Skin Boosters: Profhilo & Seventy Hyal

Profhilo & Seventy Hyal Skin Boosters

Explore two of the most advanced injectable treatments designed to hydrate, firm, and revitalise your skin.

What is Profhilo?

Profhilo is an advanced injectable skin treatment that delivers deep hydration and improves skin texture and tone. It contains high concentrations of hyaluronic acid (HA) but is not a volumising filler. Instead, it enhances overall skin quality, leaving it smoother, firmer, and more radiant.

How Does Profhilo Work?

Profhilo is injected into the deeper layers of the skin where it stimulates collagen and elastin production. It spreads beneath the skin to create long-lasting hydration and promote tissue remodeling. Ideal for the face, neck, hands, and décolletage, especially in skin showing early signs of ageing.

Key Benefits of Profhilo
  • Intense hydration and smoother skin
  • Stimulates collagen and elastin naturally
  • Non-volumising, subtle enhancement
  • Refreshed, youthful results
Profhilo Treatment Process

Profhilo is usually done over two sessions, spaced 4 weeks apart. The injections are quick, with minimal discomfort. Results begin to appear within a few days, with full effects visible in a few weeks and lasting up to 6 months.

What is Seventy Hyal?

Seventy Hyal is a next-generation skin booster that combines high molecular weight hyaluronic acid with complex ingredients to deliver intense hydration and visible skin rejuvenation. It improves firmness, elasticity, and skin texture while reducing fine lines.

How Does Seventy Hyal Work?

Seventy Hyal is injected directly into the skin where it binds moisture, providing a plump, hydrated appearance. It also stimulates the body’s natural production of collagen and elastin, helping to firm and strengthen the skin over time. It’s ideal for the face, neck, hands, and décolletage.

Key Benefits of Seventy Hyal
  • Deep, long-lasting hydration
  • Boosts collagen and elastin production
  • Smooths fine lines and improves tone
  • Natural-looking results lasting 9–12 months
Seventy Hyal Treatment Process

Seventy Hyal is administered via a series of small injections. The procedure is quick and minimally uncomfortable, with little to no downtime. Mild redness or swelling may occur but usually resolves within a few hours. Results develop over several days and improve with time.

Skin Booster Price List

  • Profhilo Full Face

    Per session: £250

    2 sessions: £400

  • Profhilo Full Face & Neck

    Per session: £350

    2 sessions: £500

  • Polynucleotides Under Eye & Profhilo Full Face

    Per session: £350

    2 sessions: £500

    Including Neck Profhilo or Polynucleotides

    Per session: £400

    2 sessions: £650

  • Seventy Hyal 2000 Full Face

    A full course of Seventy Hyal 2000 consists of 3 treatment sessions, each spaced 4 weeks apart. One session may not achieve desired results.

    Per session: £200

    3 sessions: £350

  • Seventy Hyal 200 Full Face & Neck

    A full course of Seventy Hyal 2000 consists of 3 treatment sessions, each spaced 4 weeks apart. One session may not achieve desired results.

    Per session: £250

    3 sessions: £400

  • Polynucleotides Under Eye & Seventy Hyal Full Face

    A full course of Seventy Hyal 2000 consists of 3 treatment sessions, each spaced 4 weeks apart. One session may not achieve desired results. Included under eye polynucleotides simultaneously target under eye concerns

    Per session: £300

    3 sessions: £500

    Including neck Seventy Hyal or Polynucleotides

    Per session: £350

    3 session: £600